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Smoking and vascular endothelial function Many studies have shown that the vascular endothelium-dependent relaxation response is impaired in smokers and in experimental animal models [42,43,44,45,46,47,48, 54, 55]

9 10 Yellow-stained fingers, often observed in psychiatric units and among young drug users (autopsy series), support a possible association between those conditions and tar deposition

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